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SMILES: CC1(C)CCc2c1nc1sc(C(N)=O)c(N)c1c2C1CC1

InChI Key: InChIKey=YSMMHJLWDUXYNY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293944   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))		BDBM293944
PNG
(US10106552, Compound 19)
Show SMILES CC1(C)CCc2c1nc1sc(C(N)=O)c(N)c1c2C1CC1
Show InChI InChI=1S/C16H19N3OS/c1-16(2)6-5-8-9(7-3-4-7)10-11(17)12(14(18)20)21-15(10)19-13(8)16/h7H,3-6,17H2,1-2H3,(H2,18,20)
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antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.10E+3n/an/an/an/an/an/a



Longevica Pharmaceuticals, Inc.

US Patent


Assay Description
To determine the IC50 of compounds of the invention, recombinant eEF2K was diluted in an assay buffer in the presence of calmodulin, a calcium-bindin...

US Patent US10106552 (2018)


BindingDB Entry DOI: 10.7270/Q25M67SV
More data for this
Ligand-Target Pair