BDBM293963 US10106552, Compound 38

SMILES: CC1(C)CCCc2c1nc1sc(C(N)=O)c(N)c1c2-c1cncs1

InChI Key: InChIKey=CUKYVFJLPZGLRR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293963   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM293963 (US10106552, Compound 38) Show SMILES CC1(C)CCCc2c1nc1sc(C(N)=O)c(N)c1c2-c1cncs1 Show InChI InChI=1S/C17H18N4OS2/c1-17(2)5-3-4-8-10(9-6-20-7-23-9)11-12(18)13(15(19)22)24-16(11)21-14(8)17/h6-7H,3-5,18H2,1-2H3,(H2,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Longevica Pharmaceuticals, Inc. US Patent					Assay Description To determine the IC50 of compounds of the invention, recombinant eEF2K was diluted in an assay buffer in the presence of calmodulin, a calcium-bindin...				US Patent US10106552 (2018) BindingDB Entry DOI: 10.7270/Q25M67SV
					More data for this Ligand-Target Pair