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SMILES: NC(=O)c1sc2nc3C4CCC(C4)c3c(-c3cncs3)c2c1N

InChI Key: InChIKey=GCTVOQIIGJKEBA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293968   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))		BDBM293968
PNG
(US10106552, Compound 43)
Show SMILES NC(=O)c1sc2nc3C4CCC(C4)c3c(-c3cncs3)c2c1N
Show InChI InChI=1S/C16H14N4OS2/c17-12-11-10(8-4-19-5-22-8)9-6-1-2-7(3-6)13(9)20-16(11)23-14(12)15(18)21/h4-7H,1-3,17H2,(H2,18,21)
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US Patent
n/an/a 900n/an/an/an/an/an/a



Longevica Pharmaceuticals, Inc.

US Patent


Assay Description
To determine the IC50 of compounds of the invention, recombinant eEF2K was diluted in an assay buffer in the presence of calmodulin, a calcium-bindin...

US Patent US10106552 (2018)


BindingDB Entry DOI: 10.7270/Q25M67SV
More data for this
Ligand-Target Pair