BDBM294225 (±)-3-(1-(dimethylamino)ethyl)-6-oxo-6H-benzo[c]chromen-1-yl ethyl(methyl)carbamate::US9586925, Compound FAR-01-2CA::US9586925, EXAMPLE XIX
SMILES: CCN(C)C(=O)Oc1cc(cc2oc(=O)c3ccccc3c12)C(C)N(C)C
InChI Key: InChIKey=YGXKBTHHWMVNNV-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholinesterases (Homo sapiens (Human)) | BDBM294225 ((±)-3-(1-(dimethylamino)ethyl)-6-oxo-6H-benzo[c]ch...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOBEL ILAÇ SANAYII VE TICARET A.S. US Patent | Assay Description The potential of the compounds of the present invention to inhibit acetylcholinesterase and butyrylcholinesterase enzymes were tested according to th... | US Patent US9586925 (2017) BindingDB Entry DOI: 10.7270/Q24Q7X1C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM294225 ((±)-3-(1-(dimethylamino)ethyl)-6-oxo-6H-benzo[c]ch...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
NOBEL ILAÇ SANAYII VE TICARET A.S. US Patent | Assay Description The potential of the compounds of the present invention to inhibit acetylcholinesterase and butyrylcholinesterase enzymes were tested according to th... | US Patent US9586925 (2017) BindingDB Entry DOI: 10.7270/Q24Q7X1C | |||||||||||
More data for this Ligand-Target Pair |