BDBM294408 US9586959, Compound 74
SMILES: Brc1cnc2nc(N3CCN4CCCC4C3)c3nncn3c2c1
InChI Key: InChIKey=JEWSSXKQNAONAY-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H4 receptor (Homo sapiens (Human)) | BDBM294408 (US9586959, Compound 74) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 60 | n/a | n/a | n/a | n/a | 7.5 | 25 |
C&C RESEARCH LABORATORIES US Patent | Assay Description In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac... | US Patent US9586959 (2017) BindingDB Entry DOI: 10.7270/Q2C53NWD | |||||||||||
More data for this Ligand-Target Pair |