BDBM296107 2-{4-[(5-isopropyl-pyridin-2-yl)-methyl- amino]-phenoxy}-pyrido[3,4-d]pyrimidin- 4-ol::US10112940, Example 34::US10202381, Example 34::US10208039, Example 34::US10611763, Example 34::US10815234, Example 34

SMILES: CC(C)c1ccc(nc1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1

InChI Key: InChIKey=XKBXFTPKURQNCU-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 296107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296107 (2-{4-[(5-isopropyl-pyridin-2-yl)-methyl- amino]-ph...) Show SMILES CC(C)c1ccc(nc1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C22H21N5O2/c1-14(2)15-4-9-20(24-12-15)27(3)16-5-7-17(8-6-16)29-22-25-19-13-23-11-10-18(19)21(28)26-22/h4-14H,1-3H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10112940 (2018) BindingDB Entry DOI: 10.7270/Q2X0692W
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296107 (2-{4-[(5-isopropyl-pyridin-2-yl)-methyl- amino]-ph...) Show SMILES CC(C)c1ccc(nc1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C22H21N5O2/c1-14(2)15-4-9-20(24-12-15)27(3)16-5-7-17(8-6-16)29-22-25-19-13-23-11-10-18(19)21(28)26-22/h4-14H,1-3H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (JMJD2C)(2-372) (Homo sapiens (Human))	BDBM296107 (2-{4-[(5-isopropyl-pyridin-2-yl)-methyl- amino]-ph...) Show SMILES CC(C)c1ccc(nc1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C22H21N5O2/c1-14(2)15-4-9-20(24-12-15)27(3)16-5-7-17(8-6-16)29-22-25-19-13-23-11-10-18(19)21(28)26-22/h4-14H,1-3H3,(H,25,26,28)	GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10815234 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296107 (2-{4-[(5-isopropyl-pyridin-2-yl)-methyl- amino]-ph...) Show SMILES CC(C)c1ccc(nc1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C22H21N5O2/c1-14(2)15-4-9-20(24-12-15)27(3)16-5-7-17(8-6-16)29-22-25-19-13-23-11-10-18(19)21(28)26-22/h4-14H,1-3H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10611763 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM296107 (2-{4-[(5-isopropyl-pyridin-2-yl)-methyl- amino]-ph...) Show SMILES CC(C)c1ccc(nc1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C22H21N5O2/c1-14(2)15-4-9-20(24-12-15)27(3)16-5-7-17(8-6-16)29-22-25-19-13-23-11-10-18(19)21(28)26-22/h4-14H,1-3H3,(H,25,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair