BDBM29614 6-methoxy-2-(1-pyrrolidinyl)-3-quinolinecarbonitrile::6-methoxy-2-pyrrolidin-1-yl-quinoline-3-carbonitrile::6-methoxy-2-pyrrolidin-1-ylquinoline-3-carbonitrile::6-methoxy-2-pyrrolidino-quinoline-3-carbonitrile::MLS000070501::SMR000001680::cid_649963

SMILES: COc1ccc2nc(N3CCCC3)c(cc2c1)C#N

InChI Key: InChIKey=KVIMBQUUPLPFDD-UHFFFAOYSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 29614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human))	BDBM29614 (6-methoxy-2-(1-pyrrolidinyl)-3-quinolinecarbonitri...) Show SMILES COc1ccc2nc(N3CCCC3)c(cc2c1)C#N Show InChI InChI=1S/C15H15N3O/c1-19-13-4-5-14-11(9-13)8-12(10-16)15(17-14)18-6-2-3-7-18/h4-5,8-9H,2-3,6-7H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P
					More data for this Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human))	BDBM29614 (6-methoxy-2-(1-pyrrolidinyl)-3-quinolinecarbonitri...) Show SMILES COc1ccc2nc(N3CCCC3)c(cc2c1)C#N Show InChI InChI=1S/C15H15N3O/c1-19-13-4-5-14-11(9-13)8-12(10-16)15(17-14)18-6-2-3-7-18/h4-5,8-9H,2-3,6-7H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX
					More data for this Ligand-Target Pair
mRNA interferase toxin, antitoxin is MazE (Escherichia coli str. K-12 substr. MG1655)	BDBM29614 (6-methoxy-2-(1-pyrrolidinyl)-3-quinolinecarbonitri...) Show SMILES COc1ccc2nc(N3CCCC3)c(cc2c1)C#N Show InChI InChI=1S/C15H15N3O/c1-19-13-4-5-14-11(9-13)8-12(10-16)15(17-14)18-6-2-3-7-18/h4-5,8-9H,2-3,6-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>9.90E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2TB15DB
					More data for this Ligand-Target Pair
mRNA interferase toxin, antitoxin is MazE (Escherichia coli str. K-12 substr. MG1655)	BDBM29614 (6-methoxy-2-(1-pyrrolidinyl)-3-quinolinecarbonitri...) Show SMILES COc1ccc2nc(N3CCCC3)c(cc2c1)C#N Show InChI InChI=1S/C15H15N3O/c1-19-13-4-5-14-11(9-13)8-12(10-16)15(17-14)18-6-2-3-7-18/h4-5,8-9H,2-3,6-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>9.90E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2Z31X54
					More data for this Ligand-Target Pair
BZLF2 (Human herpesvirus 4 type 2)	BDBM29614 (6-methoxy-2-(1-pyrrolidinyl)-3-quinolinecarbonitri...) Show SMILES COc1ccc2nc(N3CCCC3)c(cc2c1)C#N Show InChI InChI=1S/C15H15N3O/c1-19-13-4-5-14-11(9-13)8-12(10-16)15(17-14)18-6-2-3-7-18/h4-5,8-9H,2-3,6-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2057DCW
					More data for this Ligand-Target Pair