BDBM29668 2-(1-{[4-(2,5-Dimethyl-phenyl)-thiazol-2-yl]-hydrazono}-ethyl)-benzo[f]chromen-3-one::2-[1-[[4-(2,5-dimethylphenyl)-2-thiazolyl]hydrazinylidene]ethyl]-3-benzo[f][1]benzopyranone::2-[N-[[4-(2,5-dimethylphenyl)-1,3-thiazol-2-yl]amino]-C-methyl-carbonimidoyl]benzo[f]chromen-3-one::2-[N-[[4-(2,5-dimethylphenyl)-1,3-thiazol-2-yl]amino]-C-methylcarbonimidoyl]benzo[f]chromen-3-one::2-[N-[[4-(2,5-dimethylphenyl)thiazol-2-yl]amino]-C-methyl-carbonimidoyl]benzo[f]chromen-3-one::MLS000559785::SMR000177243::cid_3136097

SMILES: CC(N=Nc1nc(cs1)-c1cc(C)ccc1C)c1cc2c(ccc3ccccc23)oc1=O

InChI Key: InChIKey=FHACJVAIQLPBRV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29668   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human))	BDBM29668 (2-(1-{[4-(2,5-Dimethyl-phenyl)-thiazol-2-yl]-hydra...) Show SMILES CC(N=Nc1nc(cs1)-c1cc(C)ccc1C)c1cc2c(ccc3ccccc23)oc1=O |w:2.1| Show InChI InChI=1S/C26H21N3O2S/c1-15-8-9-16(2)20(12-15)23-14-32-26(27-23)29-28-17(3)21-13-22-19-7-5-4-6-18(19)10-11-24(22)31-25(21)30/h4-14,17H,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX
					More data for this Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human))	BDBM29668 (2-(1-{[4-(2,5-Dimethyl-phenyl)-thiazol-2-yl]-hydra...) Show SMILES CC(N=Nc1nc(cs1)-c1cc(C)ccc1C)c1cc2c(ccc3ccccc23)oc1=O |w:2.1| Show InChI InChI=1S/C26H21N3O2S/c1-15-8-9-16(2)20(12-15)23-14-32-26(27-23)29-28-17(3)21-13-22-19-7-5-4-6-18(19)10-11-24(22)31-25(21)30/h4-14,17H,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	7.4	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P
					More data for this Ligand-Target Pair