BDBM297392 US10112968, Compound SAH

SMILES: N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)OC=O

InChI Key: InChIKey=HIGCALLWUWOHCV-BAYCTPFLSA-N

Data: 1 KI  1 Kd  1 K_off  1 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 297392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase, H3 lysine-79 specific (Homo sapiens (Human))	BDBM297392 (US10112968, Compound SAH) Show SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)OC=O |r| Show InChI InChI=1S/C14H20N6O5S/c15-8(24-6-21)1-2-26-3-7-10(22)11(23)14(25-7)20-5-19-9-12(16)17-4-18-13(9)20/h4-8,10-11,14,22-23H,1-3,15H2,(H2,16,17,18)/t7-,8-,10-,11-,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	320	n/a	n/a	71	n/a	0.100	1.40E+6	n/a	n/a
Epizyme, Inc. US Patent					Assay Description Unless otherwise indicated, assays of DOT1L enzymatic activity were performed under balanced conditions (all substrates present at concentrations equ...				US Patent US10112968 (2018) BindingDB Entry DOI: 10.7270/Q20R9RFJ
					More data for this Ligand-Target Pair