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SMILES: O[C@@H](CNC(=O)COc1cccc2cccnc12)CN1Cc2ccccc2C1

InChI Key: InChIKey=DOONEOBBMQKESC-IBGZPJMESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM297725 ((S)No FitN-(2-hydroxy-3-(isoindolin-2-yl)propyl)-2...) Show SMILES O[C@@H](CNC(=O)COc1cccc2cccnc12)CN1Cc2ccccc2C1 |r| Show InChI InChI=1S/C22H23N3O3/c26-19(14-25-12-17-5-1-2-6-18(17)13-25)11-24-21(27)15-28-20-9-3-7-16-8-4-10-23-22(16)20/h1-10,19,26H,11-15H2,(H,24,27)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description General Materials.S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), bicine, KCl, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG)...				US Patent US9732072 (2017) BindingDB Entry DOI: 10.7270/Q2FF3VGW
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM297725 ((S)No FitN-(2-hydroxy-3-(isoindolin-2-yl)propyl)-2...) Show SMILES O[C@@H](CNC(=O)COc1cccc2cccnc12)CN1Cc2ccccc2C1 |r| Show InChI InChI=1S/C22H23N3O3/c26-19(14-25-12-17-5-1-2-6-18(17)13-25)11-24-21(27)15-28-20-9-3-7-16-8-4-10-23-22(16)20/h1-10,19,26H,11-15H2,(H,24,27)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10118918 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZK6
					More data for this Ligand-Target Pair