null

SMILES: OC(CC(Cc1ccc(c(Cl)c1)-c1cc(Cl)ccc1F)NC(=O)C(O)=O)C(O)=O

InChI Key: InChIKey=PNEXKZXWXPXMQL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298301   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin/Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM298301 (US10123984, Example 5-13 | US20230285340, Example ...) Show SMILES OC(CC(Cc1ccc(c(Cl)c1)-c1cc(Cl)ccc1F)NC(=O)C(O)=O)C(O)=O Show InChI InChI=1S/C19H16Cl2FNO6/c20-10-2-4-15(22)13(7-10)12-3-1-9(6-14(12)21)5-11(8-16(24)18(26)27)23-17(25)19(28)29/h1-4,6-7,11,16,24H,5,8H2,(H,23,25)(H,26,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem		<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2PR8136
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM298301 (US10123984, Example 5-13 | US20230285340, Example ...) Show SMILES OC(CC(Cc1ccc(c(Cl)c1)-c1cc(Cl)ccc1F)NC(=O)C(O)=O)C(O)=O Show InChI InChI=1S/C19H16Cl2FNO6/c20-10-2-4-15(22)13(7-10)12-3-1-9(6-14(12)21)5-11(8-16(24)18(26)27)23-17(25)19(28)29/h1-4,6-7,11,16,24H,5,8H2,(H,23,25)(H,26,27)(H,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THERAVANCE BIOPHARMA R&D IP, LLC US Patent					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				US Patent US10123984 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DVB
					More data for this Ligand-Target Pair