null

SMILES: CCCCOC(=O)[C@H](CO)C[C@@H](Cc1ccc(cc1)-c1ccccc1F)NC(=O)C(O)=O

InChI Key: InChIKey=IMWFTXYTKALWMO-RBUKOAKNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin/Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM298306 (US10123984, Example 7B | US11547687, Example 7B) Show SMILES CCCCOC(=O)[C@H](CO)C[C@@H](Cc1ccc(cc1)-c1ccccc1F)NC(=O)C(O)=O |r| Show InChI InChI=1S/C24H28FNO6/c1-2-3-12-32-24(31)18(15-27)14-19(26-22(28)23(29)30)13-16-8-10-17(11-9-16)20-6-4-5-7-21(20)25/h4-11,18-19,27H,2-3,12-15H2,1H3,(H,26,28)(H,29,30)/t18-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BG2STK
					More data for this Ligand-Target Pair
Neprilysin (Homo sapiens (Human))	BDBM298306 (US10123984, Example 7B | US11547687, Example 7B) Show SMILES CCCCOC(=O)[C@H](CO)C[C@@H](Cc1ccc(cc1)-c1ccccc1F)NC(=O)C(O)=O |r| Show InChI InChI=1S/C24H28FNO6/c1-2-3-12-32-24(31)18(15-27)14-19(26-22(28)23(29)30)13-16-8-10-17(11-9-16)20-6-4-5-7-21(20)25/h4-11,18-19,27H,2-3,12-15H2,1H3,(H,26,28)(H,29,30)/t18-,19+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THERAVANCE BIOPHARMA R&D IP, LLC US Patent					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				US Patent US10123984 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DVB
					More data for this Ligand-Target Pair