BDBM298327 US10123984, Comparative Compound A
SMILES: C[C@H](C[C@H](NC(=O)C(O)=O)c1ccc(cc1)-c1ccccc1)C(O)=O
InChI Key: InChIKey=QRMCBHUGKNLYBI-WBMJQRKESA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neprilysin (Homo sapiens (Human)) | BDBM298327 (US10123984, Comparative Compound A ) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
THERAVANCE BIOPHARMA R&D IP, LLC US Patent | Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa... | US Patent US10123984 (2018) BindingDB Entry DOI: 10.7270/Q2KK9DVB | |||||||||||
More data for this Ligand-Target Pair |