BDBM298351 US10124009, Compound 7
SMILES: Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)OC\C(Br)=C(/Br)CO)c1nnc(C)n-21)c1ccc(Cl)cc1
InChI Key: InChIKey=KRCYZWORMBQUNG-GVJQPLCZSA-N
Data: 2 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 Isoform C (Homo sapiens (Human)) | BDBM298351 (US10124009, Compound 7) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM298351 (US10124009, Compound 7) | PDB KEGG B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a |
Tensha Therapeutics, Inc. US Patent | Assay Description A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain... | US Patent US10124009 (2018) BindingDB Entry DOI: 10.7270/Q26975MC | |||||||||||
More data for this Ligand-Target Pair |