BDBM29872 phenoxyacetic acid-ether, 14
SMILES: Cc1c(C)c(Sc2ccc(COc3ccc(cc3)C(F)(F)F)cc2OCc2cccnc2)ccc1OCC(O)=O
InChI Key: InChIKey=HIWVJWKNISSDFF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM29872 (phenoxyacetic acid-ether, 14) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 36 | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a |
Amgen | Assay Description The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f... | Bioorg Med Chem Lett 19: 3550-4 (2009) Article DOI: 10.1016/j.bmcl.2009.04.151 BindingDB Entry DOI: 10.7270/Q2NK3CC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human)) | BDBM29872 (phenoxyacetic acid-ether, 14) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.30E+3 | -7.94 | n/a | n/a | >1.00E+4 | n/a | n/a | 7.1 | 22 |
Amgen | Assay Description The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f... | Bioorg Med Chem Lett 19: 3550-4 (2009) Article DOI: 10.1016/j.bmcl.2009.04.151 BindingDB Entry DOI: 10.7270/Q2NK3CC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM29872 (phenoxyacetic acid-ether, 14) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.10E+3 | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Amgen | Assay Description The human PPARgamma ligand binding was directly measured using a filtration assay in a UniFilter 350 96-well assay plate (Polyfiltronics). The reacti... | Bioorg Med Chem Lett 19: 3550-4 (2009) Article DOI: 10.1016/j.bmcl.2009.04.151 BindingDB Entry DOI: 10.7270/Q2NK3CC0 | |||||||||||
More data for this Ligand-Target Pair |