null

SMILES: Cc1c(C)c(Sc2ccc(COc3ccc(cc3)C(F)(F)F)cc2OCc2ccncc2)ccc1OCC(O)=O

InChI Key: InChIKey=QOVRZVRUKFJQMJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29873   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM29873 (phenoxyacetic acid-ether, 15) Show SMILES Cc1c(C)c(Sc2ccc(COc3ccc(cc3)C(F)(F)F)cc2OCc2ccncc2)ccc1OCC(O)=O Show InChI InChI=1S/C30H26F3NO5S/c1-19-20(2)27(10-8-25(19)39-18-29(35)36)40-28-9-3-22(15-26(28)38-16-21-11-13-34-14-12-21)17-37-24-6-4-23(5-7-24)30(31,32)33/h3-15H,16-18H2,1-2H3,(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a
Amgen					Assay Description The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...				Bioorg Med Chem Lett 19: 3550-4 (2009) Article DOI: 10.1016/j.bmcl.2009.04.151 BindingDB Entry DOI: 10.7270/Q2NK3CC0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM29873 (phenoxyacetic acid-ether, 15) Show SMILES Cc1c(C)c(Sc2ccc(COc3ccc(cc3)C(F)(F)F)cc2OCc2ccncc2)ccc1OCC(O)=O Show InChI InChI=1S/C30H26F3NO5S/c1-19-20(2)27(10-8-25(19)39-18-29(35)36)40-28-9-3-22(15-26(28)38-16-21-11-13-34-14-12-21)17-37-24-6-4-23(5-7-24)30(31,32)33/h3-15H,16-18H2,1-2H3,(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	-7.94	n/a	n/a	>1.00E+4	n/a	n/a	7.1	22
Amgen					Assay Description The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...				Bioorg Med Chem Lett 19: 3550-4 (2009) Article DOI: 10.1016/j.bmcl.2009.04.151 BindingDB Entry DOI: 10.7270/Q2NK3CC0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM29873 (phenoxyacetic acid-ether, 15) Show SMILES Cc1c(C)c(Sc2ccc(COc3ccc(cc3)C(F)(F)F)cc2OCc2ccncc2)ccc1OCC(O)=O Show InChI InChI=1S/C30H26F3NO5S/c1-19-20(2)27(10-8-25(19)39-18-29(35)36)40-28-9-3-22(15-26(28)38-16-21-11-13-34-14-12-21)17-37-24-6-4-23(5-7-24)30(31,32)33/h3-15H,16-18H2,1-2H3,(H,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Amgen					Assay Description The human PPARgamma ligand binding was directly measured using a filtration assay in a UniFilter 350 96-well assay plate (Polyfiltronics). The reacti...				Bioorg Med Chem Lett 19: 3550-4 (2009) Article DOI: 10.1016/j.bmcl.2009.04.151 BindingDB Entry DOI: 10.7270/Q2NK3CC0
					More data for this Ligand-Target Pair