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SMILES: CCS(=O)(=O)c1ccc(cc1)-c1ccc2[C@H](c3cccc(F)c3Oc2n1)C(C)(C)C(=O)NC(N)=O

InChI Key: InChIKey=FGQNQHQFMTZDHM-FQEVSTJZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299266   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM299266
PNG
(US9593113, Example 31)
Show SMILES CCS(=O)(=O)c1ccc(cc1)-c1ccc2[C@H](c3cccc(F)c3Oc2n1)C(C)(C)C(=O)NC(N)=O |r|
Show InChI InChI=1S/C25H24FN3O5S/c1-4-35(32,33)15-10-8-14(9-11-15)19-13-12-17-20(25(2,3)23(30)29-24(27)31)16-6-5-7-18(26)21(16)34-22(17)28-19/h5-13,20H,4H2,1-3H3,(H3,27,29,30,31)/t20-/m0/s1
PDB

KEGG

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PC cid
PC sid
UniChem
US Patent
 0.430n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Binding Assay (I):In order to assess the affinity of test compounds for the human glucocorticoid receptor, a commercially available kit was used (Glu...

US Patent US9593113 (2017)


BindingDB Entry DOI: 10.7270/Q2833V3Z
More data for this
Ligand-Target Pair