BDBM299628 (2S,4S)-5-(3′-Bromobiphenyl-4-yl)-2-methoxymethyl-4-[(3H-[1,2,3]triazole-4-carbonyl)amino]pentanoic Acid::US9593110, Example 80

SMILES: COC[C@H](C[C@@H](Cc1ccc(cc1)-c1cccc(Br)c1)NC(=O)c1cnn[nH]1)C(O)=O

InChI Key:

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299628   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM299628 ((2S,4S)-5-(3′-Bromobiphenyl-4-yl)-2-methoxym...) Show SMILES COC[C@H](C[C@@H](Cc1ccc(cc1)-c1cccc(Br)c1)NC(=O)c1cnn[nH]1)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravence Biopharma R&D IP, LLC US Patent					Assay Description Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...				US Patent US9593110 (2017) BindingDB Entry DOI: 10.7270/Q2MC9224
					More data for this Ligand-Target Pair