BDBM29984 arylpyrazole, 29
SMILES: Cc1c(CNC2CCC(F)(F)C2)nn(c1-c1ccc(C)nc1)-c1ncccc1Cl
InChI Key: InChIKey=DMJMZMXUINSYIJ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM29984 (arylpyrazole, 29) | PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Pharmaceutical Co. | Assay Description Binding affinity to the hERG K+ channel was measured by displacement of [35S]-radiolabeled MK499 in membranes derived from HEK 293 cells stably trans... | Bioorg Med Chem Lett 19: 3627-31 (2009) Article DOI: 10.1016/j.bmcl.2009.04.116 BindingDB Entry DOI: 10.7270/Q289145G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM29984 (arylpyrazole, 29) | PDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.30 | n/a | 4.5 | n/a | n/a | n/a | n/a |
Banyu Pharmaceutical Co. | Assay Description Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra... | Bioorg Med Chem Lett 19: 3627-31 (2009) Article DOI: 10.1016/j.bmcl.2009.04.116 BindingDB Entry DOI: 10.7270/Q289145G | |||||||||||
More data for this Ligand-Target Pair |