BDBM299917 4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)pyridin-3- yl]oxy}methyl) piperidin-1-yl]-N- tert-butyl-6-[(1- cyanocyclopropyl) methoxy]-1,3,5- triazine-2- carboxamide::US9593097, Example 287

SMILES: Cn1cnc(c1)-c1cnc(N)c(OCC2CCN(CC2)c2nc(OCC3(CC3)C#N)nc(n2)C(=O)NC(C)(C)C)c1

InChI Key: InChIKey=MWGFYEOQJKMEBL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM299917 (4-[4-({[2-amino-5- (1-methyl-1H- imidazol-4- yl)py...) Show SMILES Cn1cnc(c1)-c1cnc(N)c(OCC2CCN(CC2)c2nc(OCC3(CC3)C#N)nc(n2)C(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C28H36N10O3/c1-27(2,3)36-24(39)23-33-25(35-26(34-23)41-16-28(15-29)7-8-28)38-9-5-18(6-10-38)14-40-21-11-19(12-31-22(21)30)20-13-37(4)17-32-20/h11-13,17-18H,5-10,14,16H2,1-4H3,(H2,30,31)(H,36,39)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...				US Patent US9593097 (2017) BindingDB Entry DOI: 10.7270/Q2GM89BD
					More data for this Ligand-Target Pair