BDBM299995 4-[(1- cyanocyclopropyl) methoxy]-6-[4-(4- methoxy-1H- pyrrolo[2,3- b]pyridin-3- yl)piperidin-1-yl]- N-(2,2,2- trifluoroethyl)- 1,3,5-triazine-2- carboxamide::US9593097, Example 366

SMILES: COc1ccnc2[nH]nc(C3CCN(CC3)c3nc(OCC4(CC4)C#N)nc(n3)C(=O)NCC(F)(F)F)c12

InChI Key: InChIKey=KSUAKJRVYBTTOR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM299995 (4-[(1- cyanocyclopropyl) methoxy]-6-[4-(4- methoxy...) Show SMILES COc1ccnc2[nH]nc(C3CCN(CC3)c3nc(OCC4(CC4)C#N)nc(n3)C(=O)NCC(F)(F)F)c12 Show InChI InChI=1S/C23H24F3N9O3/c1-37-14-2-7-28-17-15(14)16(33-34-17)13-3-8-35(9-4-13)20-30-18(19(36)29-11-23(24,25)26)31-21(32-20)38-12-22(10-27)5-6-22/h2,7,13H,3-6,8-9,11-12H2,1H3,(H,29,36)(H,28,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...				US Patent US9593097 (2017) BindingDB Entry DOI: 10.7270/Q2GM89BD
					More data for this Ligand-Target Pair