BDBM300063 N-[(2R)-3- hydroxy-3- methylbutan-2-yl]- 4-{[(2R)-1- methoxypropan-2- yl]oxy}-6-[4-(4- methoxy-1H- pyrrolo[2,3- b]pyridin-3- yl)piperidin-1-yl]- 1,3,5-triazine-2- carboxamide::US9593097, Example 443

SMILES: COC[C@@H](C)Oc1nc(nc(n1)C(=O)N[C@H](C)C(C)(C)O)N1CCC(CC1)c1c[nH]c2nccc(OC)c12

InChI Key:

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM300063 (N-[(2R)-3- hydroxy-3- methylbutan-2-yl]- 4-{[(2R)-...) Show SMILES COC[C@@H](C)Oc1nc(nc(n1)C(=O)N[C@H](C)C(C)(C)O)N1CCC(CC1)c1c[nH]c2nccc(OC)c12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...				US Patent US9593097 (2017) BindingDB Entry DOI: 10.7270/Q2GM89BD
					More data for this Ligand-Target Pair