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BDBM300312 US9593110, 9-4

SMILES: CCOC[C@H](C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1cc(OC)no1)C(O)=O

InChI Key: InChIKey=WWEBQPPZXRJSMW-PZJWPPBQSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300312   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Homo sapiens (Human))		BDBM300312
PNG
(US9593110, 9-4)
Show SMILES CCOC[C@H](C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1cc(OC)no1)C(O)=O
Show InChI InChI=1S/C25H27ClN2O6/c1-3-33-15-19(25(30)31)13-21(27-24(29)22-14-23(32-2)28-34-22)11-16-7-9-17(10-8-16)18-5-4-6-20(26)12-18/h4-10,12,14,19,21H,3,11,13,15H2,1-2H3,(H,27,29)(H,30,31)/t19-,21+/m0/s1
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KEGG

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PC cid
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US Patent
<1n/an/an/an/an/an/an/an/a



Theravence Biopharma R&D IP, LLC

US Patent


Assay Description
Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...

US Patent US9593110 (2017)


BindingDB Entry DOI: 10.7270/Q2MC9224
More data for this
Ligand-Target Pair