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InChI Key: InChIKey=JEDXLJDLMAMYIV-VQIMIIECSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300353   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Homo sapiens (Human))		BDBM300353
PNG
(US9593110, 16-29)
Show InChI InChI=1S/C22H20ClFN4O3/c23-15-6-7-18(24)17(11-15)14-4-2-13(3-5-14)10-16(12-19(25)22(30)31)28-21(29)20-26-8-1-9-27-20/h1-9,11,16,19H,10,12,25H2,(H,28,29)(H,30,31)/t16-,19-/m1/s1
PDB

KEGG

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PC cid
PC sid
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US Patent
<1n/an/an/an/an/an/an/an/a



Theravence Biopharma R&D IP, LLC

US Patent


Assay Description
Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...

US Patent US9593110 (2017)


BindingDB Entry DOI: 10.7270/Q2MC9224
More data for this
Ligand-Target Pair