BDBM300355 US9593110, 52-1

SMILES:

InChI Key: InChIKey=ZWZGVLPNUIMUHJ-IEBWSBKVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM300355 (US9593110, 52-1) Show SMILES Show InChI InChI=1S/C24H21ClFN3O3S/c1-14-10-22(33-29-14)23(30)28-19(12-17(8-9-27)24(31)32)11-15-2-4-16(5-3-15)20-13-18(25)6-7-21(20)26/h2-7,10,13,17,19H,8,11-12H2,1H3,(H,28,30)(H,31,32)/t17-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravence Biopharma R&D IP, LLC US Patent					Assay Description Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...				US Patent US9593110 (2017) BindingDB Entry DOI: 10.7270/Q2MC9224
					More data for this Ligand-Target Pair