BDBM300370 US10130619, Example 46

SMILES: COc1cc(cnc1O[C@@H](C)c1ccccn1)C(=O)Nc1nnc(s1)-c1ccncc1

InChI Key: InChIKey=QJJJYLAYWFPJBN-ZDUSSCGKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH oxidase 1 (Homo sapiens (Human))	BDBM300370 (US10130619, Example 46) Show SMILES COc1cc(cnc1O[C@@H](C)c1ccccn1)C(=O)Nc1nnc(s1)-c1ccncc1 |r| Show InChI InChI=1S/C21H18N6O3S/c1-13(16-5-3-4-8-23-16)30-19-17(29-2)11-15(12-24-19)18(28)25-21-27-26-20(31-21)14-6-9-22-10-7-14/h3-13H,1-2H3,(H,25,27,28)/t13-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GENKYOTEX SUISSE SA US Patent					Assay Description All solutions were placed on ice and protected from light. The final concentration in the 1x hNOX1 membrane fluorescent assay buffer was PBS pH7, 6 &...				US Patent US10130619 (2018) BindingDB Entry DOI: 10.7270/Q2Q52RPP
					More data for this Ligand-Target Pair