null

SMILES: CN(C)C1(CC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F

InChI Key: InChIKey=YDPJEULZEGJWCD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Homo sapiens (Human))	BDBM300609 (3-({[1- (dimethylamino)cyclopropyl] carbonyl}amino...) Show SMILES CN(C)C1(CC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F Show InChI InChI=1S/C25H22F4N4O3/c1-33(2)24(11-12-24)23(35)32-20-13-15(7-10-21(20)36-25(27,28)29)22(34)31-16-8-9-19(30-14-16)17-5-3-4-6-18(17)26/h3-10,13-14H,11-12H2,1-2H3,(H,31,34)(H,32,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300609 (3-({[1- (dimethylamino)cyclopropyl] carbonyl}amino...) Show SMILES CN(C)C1(CC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F Show InChI InChI=1S/C25H22F4N4O3/c1-33(2)24(11-12-24)23(35)32-20-13-15(7-10-21(20)36-25(27,28)29)22(34)31-16-8-9-19(30-14-16)17-5-3-4-6-18(17)26/h3-10,13-14H,11-12H2,1-2H3,(H,31,34)(H,32,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	362	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair