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SMILES: OCC(CC(Cc1ccccc1)NC(=O)c1cc(n[nH]1)C(=O)N1CCC1)C(O)=O

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300728   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Homo sapiens (Human))		BDBM300728
PNG
(US10130642, Example 4-24)
Show SMILES OCC(CC(Cc1ccccc1)NC(=O)c1cc(n[nH]1)C(=O)N1CCC1)C(O)=O
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US Patent
<1n/an/an/an/an/an/an/an/a



THERAVANCE BIOPHARMA R&D IP, LLC

US Patent


Assay Description
Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...

US Patent US10130642 (2018)


BindingDB Entry DOI: 10.7270/Q29Z96ZH
More data for this
Ligand-Target Pair