BDBM300928 US10131658, Compound 63
SMILES: OC(=O)[C@H](Cc1ccc(NC(=O)CCCc2ccc3CCCNc3n2)cc1)NC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccccc1
InChI Key: InChIKey=TUXAORRGUIOJAM-NSOVKSMOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha5beta1 (Homo sapiens (Human)) | BDBM300928 (US10131658, Compound 63) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 505 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of California US Patent | Assay Description A panel of cell lines and integrin ligands were developed to allow rapid examination of potency and specificity of inhibitors against all 8 integrins... | US Patent US10131658 (2018) BindingDB Entry DOI: 10.7270/Q2SX6G8Q | |||||||||||
More data for this Ligand-Target Pair |