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SMILES: COc1ccc(cc1F)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC(N)CC1

InChI Key: InChIKey=SNAAPCORVMHCHT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301091   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))		BDBM301091
PNG
(4-[2-(4-aminopiperidin-1-yl)-5-(3- fluoro-4-methox...)
Show SMILES COc1ccc(cc1F)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC(N)CC1
Show InChI InChI=1S/C23H22FN5O/c1-30-21-7-6-17(12-20(21)24)19-14-27-23(29-10-8-18(26)9-11-29)28-22(19)16-4-2-15(13-25)3-5-16/h2-7,12,14,18H,8-11,26H2,1H3
PDB
MMDB

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PC cid
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US Patent
n/an/a<10n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...

US Patent US10131664 (2018)


BindingDB Entry DOI: 10.7270/Q2JD4ZV1
More data for this
Ligand-Target Pair