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SMILES: Cn1cnc2cc(ccc12)-c1cnc(nc1-c1ccc(C#N)c(F)c1)N1CCC(N)CC1

InChI Key: InChIKey=UNDHMJNRZKVHLE-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301094   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))		BDBM301094
PNG
(4-[2-(4-aminopiperidin-1-yl)-5-(1- methylbenzimida...)
Show SMILES Cn1cnc2cc(ccc12)-c1cnc(nc1-c1ccc(C#N)c(F)c1)N1CCC(N)CC1
Show InChI InChI=1S/C24H22FN7/c1-31-14-29-21-11-15(4-5-22(21)31)19-13-28-24(32-8-6-18(27)7-9-32)30-23(19)16-2-3-17(12-26)20(25)10-16/h2-5,10-11,13-14,18H,6-9,27H2,1H3
PDB
MMDB

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PC cid
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US Patent
n/an/a<10n/an/an/an/an/an/a



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...

US Patent US10131664 (2018)


BindingDB Entry DOI: 10.7270/Q2JD4ZV1
More data for this
Ligand-Target Pair