BDBM301956 3-(3-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-yl)propyl)-1H-indole-5-carbonitrile::US9598401, Example 10

SMILES: COc1cc(OC)nc(n1)N1CCN(CCCc2c[nH]c3ccc(cc23)C#N)CC1

InChI Key: InChIKey=YYSGFKYOICNQAC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 301956   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301956 (3-(3-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C22H26N6O2/c1-29-20-13-21(30-2)26-22(25-20)28-10-8-27(9-11-28)7-3-4-17-15-24-19-6-5-16(14-23)12-18(17)19/h5-6,12-13,15,24H,3-4,7-11H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM301956 (3-(3-(4-(4,6-Dimethoxypyrimidin-2-yl)piperazin-1-y...) Show SMILES COc1cc(OC)nc(n1)N1CCN(CCCc2c[nH]c3ccc(cc23)C#N)CC1 Show InChI InChI=1S/C22H26N6O2/c1-29-20-13-21(30-2)26-22(25-20)28-10-8-27(9-11-28)7-3-4-17-15-24-19-6-5-16(14-23)12-18(17)19/h5-6,12-13,15,24H,3-4,7-11H2,1-2H3	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Cell membrane homogenates (24 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]methyl-spiperone in the absence or presence of...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair