BDBM301957 3-(4-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl)butyl)-1H-indole::US9598401, Example 11

SMILES: Cc1cc(C)nc(n1)N1CCN(CCCCc2c[nH]c3ccccc23)CC1

InChI Key: InChIKey=MFEYFMBNXHEZNH-UHFFFAOYSA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301957   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301957 (3-(4-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl...) Show SMILES Cc1cc(C)nc(n1)N1CCN(CCCCc2c[nH]c3ccccc23)CC1 Show InChI InChI=1S/C22H29N5/c1-17-15-18(2)25-22(24-17)27-13-11-26(12-14-27)10-6-5-7-19-16-23-21-9-4-3-8-20(19)21/h3-4,8-9,15-16,23H,5-7,10-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair