BDBM301965 3-(3-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl)propyl)-5-fluoro-1H-indole::US9598401, Example 19

SMILES: Cc1cc(C)nc(n1)N1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1

InChI Key: InChIKey=QGJIFPGQFKHCGK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM301965 (3-(3-(4-(4,6-Dimethylpyrimidin-2-yl)piperazin-1-yl...) Show SMILES Cc1cc(C)nc(n1)N1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1 Show InChI InChI=1S/C21H26FN5/c1-15-12-16(2)25-21(24-15)27-10-8-26(9-11-27)7-3-4-17-14-23-20-6-5-18(22)13-19(17)20/h5-6,12-14,23H,3-4,7-11H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...				US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F
					More data for this Ligand-Target Pair