BDBM301982 Ethyl 2-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperazin-1-yl)-4-methylthiazole-5-carboxylate::US9598401, Example 38
SMILES: CCOC(=O)c1sc(nc1C)N1CCN(CCCc2c[nH]c3ccc(F)cc23)CC1
InChI Key: InChIKey=FKJYOHQRGCBKAB-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM301982 (Ethyl 2-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piper...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SUNSHINE LAKE PHARMA CO., LTD. US Patent | Assay Description Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o... | US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dopamine D2 S receptor (Homo sapiens (Human)) | BDBM301982 (Ethyl 2-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piper...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SUNSHINE LAKE PHARMA CO., LTD. US Patent | Assay Description Cell membrane homogenates (24 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]methyl-spiperone in the absence or presence of... | US Patent US9598401 (2017) BindingDB Entry DOI: 10.7270/Q2GH9M1F | |||||||||||
More data for this Ligand-Target Pair |