null

SMILES: NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)Nc1cc(F)cc(F)c1

InChI Key: InChIKey=MKRCTXCJLAQGIZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM302465 (N5-(3,5-Difluorophenyl)- 2-(3-fluorophenyl)-6,7- d...) Show SMILES NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)Nc1cc(F)cc(F)c1 Show InChI InChI=1S/C20H16F3N5O2/c21-12-3-1-2-11(6-12)18-17(19(24)29)16-10-27(4-5-28(16)26-18)20(30)25-15-8-13(22)7-14(23)9-15/h1-3,6-9H,4-5,10H2,(H2,24,29)(H,25,30)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM302465 (N5-(3,5-Difluorophenyl)- 2-(3-fluorophenyl)-6,7- d...) Show SMILES NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)Nc1cc(F)cc(F)c1 Show InChI InChI=1S/C20H16F3N5O2/c21-12-3-1-2-11(6-12)18-17(19(24)29)16-10-27(4-5-28(16)26-18)20(30)25-15-8-13(22)7-14(23)9-15/h1-3,6-9H,4-5,10H2,(H2,24,29)(H,25,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair