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SMILES: NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F

InChI Key: InChIKey=FBRUNCHNVKBHIP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302469   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM302469 (N5-(4-Chloro-3- (trifluoromethyl)phenyl)- 2-(3-flu...) Show SMILES NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C21H16ClF4N5O2/c22-15-5-4-13(9-14(15)21(24,25)26)28-20(33)30-6-7-31-16(10-30)17(19(27)32)18(29-31)11-2-1-3-12(23)8-11/h1-5,8-9H,6-7,10H2,(H2,27,32)(H,28,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM302469 (N5-(4-Chloro-3- (trifluoromethyl)phenyl)- 2-(3-flu...) Show SMILES NC(=O)c1c2CN(CCn2nc1-c1cccc(F)c1)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C21H16ClF4N5O2/c22-15-5-4-13(9-14(15)21(24,25)26)28-20(33)30-6-7-31-16(10-30)17(19(27)32)18(29-31)11-2-1-3-12(23)8-11/h1-5,8-9H,6-7,10H2,(H2,27,32)(H,28,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
					More data for this Ligand-Target Pair