BDBM303011 (2S,4R)-1-(2-(3- acetyl-5-(pyrimidin-5- ylamino)-1H-indol-1- yl)acetyl)-N-(2-ethyl- 3-oxoisoindolin-5-yl)- 4-fluoropyrrolidine-2- carboxamide::US10660876, Cmpd No. 23::US9598446, Compound 23

SMILES: CCN1Cc2ccc(NC(=O)[C@@H]3C[C@@H](F)CN3C(=O)Cn3cc(C(C)=O)c4cc(Nc5cncnc5)ccc34)cc2C1=O

InChI Key: InChIKey=ATPSKHFIIPPEIS-NGOKVRLYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM303011 ((2S,4R)-1-(2-(3- acetyl-5-(pyrimidin-5- ylamino)-1...) Show SMILES CCN1Cc2ccc(NC(=O)[C@@H]3C[C@@H](F)CN3C(=O)Cn3cc(C(C)=O)c4cc(Nc5cncnc5)ccc34)cc2C1=O |r| Show InChI InChI=1S/C31H30FN7O4/c1-3-37-13-19-4-5-22(9-24(19)31(37)43)36-30(42)28-8-20(32)14-39(28)29(41)16-38-15-26(18(2)40)25-10-21(6-7-27(25)38)35-23-11-33-17-34-12-23/h4-7,9-12,15,17,20,28,35H,3,8,13-14,16H2,1-2H3,(H,36,42)/t20-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Achillion Pharmaceuticals, Inc. US Patent					Assay Description Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...				US Patent US10660876 (2020)
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM303011 ((2S,4R)-1-(2-(3- acetyl-5-(pyrimidin-5- ylamino)-1...) Show SMILES CCN1Cc2ccc(NC(=O)[C@@H]3C[C@@H](F)CN3C(=O)Cn3cc(C(C)=O)c4cc(Nc5cncnc5)ccc34)cc2C1=O |r| Show InChI InChI=1S/C31H30FN7O4/c1-3-37-13-19-4-5-22(9-24(19)31(37)43)36-30(42)28-8-20(32)14-39(28)29(41)16-38-15-26(18(2)40)25-10-21(6-7-27(25)38)35-23-11-33-17-34-12-23/h4-7,9-12,15,17,20,28,35H,3,8,13-14,16H2,1-2H3,(H,36,42)/t20-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ACHILLION PHARMACEUTICALS, INC. US Patent					Assay Description Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...				US Patent US9598446 (2017) BindingDB Entry DOI: 10.7270/Q2ST7RWF
					More data for this Ligand-Target Pair