BDBM303012 (2S,4R)-1-(2-(3- acetyl-5-(pyrimidin-5- ylamino)-1H-indol-1- yl)acetyl)-N-(2,2- dimethyl-2,3- dihydrobenzofuran-7- yl)-4- fluoropyrrolidine-2- carboxamide::US10660876, Cmpd No. 24::US9598446, Compound 24

SMILES: CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc3CC(C)(C)Oc23)c2ccc(Nc3cncnc3)cc12

InChI Key: InChIKey=WZHHICLBIJGXRJ-HRFSGMKKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM303012 ((2S,4R)-1-(2-(3- acetyl-5-(pyrimidin-5- ylamino)-1...) Show SMILES CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc3CC(C)(C)Oc23)c2ccc(Nc3cncnc3)cc12 |r| Show InChI InChI=1S/C31H31FN6O4/c1-18(39)24-15-37(26-8-7-21(10-23(24)26)35-22-12-33-17-34-13-22)16-28(40)38-14-20(32)9-27(38)30(41)36-25-6-4-5-19-11-31(2,3)42-29(19)25/h4-8,10,12-13,15,17,20,27,35H,9,11,14,16H2,1-3H3,(H,36,41)/t20-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Achillion Pharmaceuticals, Inc. US Patent					Assay Description Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...				US Patent US10660876 (2020)
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM303012 ((2S,4R)-1-(2-(3- acetyl-5-(pyrimidin-5- ylamino)-1...) Show SMILES CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc3CC(C)(C)Oc23)c2ccc(Nc3cncnc3)cc12 |r| Show InChI InChI=1S/C31H31FN6O4/c1-18(39)24-15-37(26-8-7-21(10-23(24)26)35-22-12-33-17-34-13-22)16-28(40)38-14-20(32)9-27(38)30(41)36-25-6-4-5-19-11-31(2,3)42-29(19)25/h4-8,10,12-13,15,17,20,27,35H,9,11,14,16H2,1-3H3,(H,36,41)/t20-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
ACHILLION PHARMACEUTICALS, INC. US Patent					Assay Description Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...				US Patent US9598446 (2017) BindingDB Entry DOI: 10.7270/Q2ST7RWF
					More data for this Ligand-Target Pair