null

SMILES: CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NC2CCc3c2c(F)ccc3F)c2ccc(Nc3cncnc3)cc12

InChI Key: InChIKey=YHSCFRRYKWOEIC-CLFDNNGGSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303046   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM303046 ((2S,4R)-1-(2-(3- acetyl-5-(pyrimidin-5- ylamino)-1...) Show SMILES CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NC2CCc3c2c(F)ccc3F)c2ccc(Nc3cncnc3)cc12 |r| Show InChI InChI=1S/C30H27F3N6O3/c1-16(40)22-13-38(26-7-2-18(9-21(22)26)36-19-10-34-15-35-11-19)14-28(41)39-12-17(31)8-27(39)30(42)37-25-6-3-20-23(32)4-5-24(33)29(20)25/h2,4-5,7,9-11,13,15,17,25,27,36H,3,6,8,12,14H2,1H3,(H,37,42)/t17-,25?,27+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Achillion Pharmaceuticals, Inc. US Patent					Assay Description Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...				US Patent US10660876 (2020)
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM303046 ((2S,4R)-1-(2-(3- acetyl-5-(pyrimidin-5- ylamino)-1...) Show SMILES CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NC2CCc3c2c(F)ccc3F)c2ccc(Nc3cncnc3)cc12 |r| Show InChI InChI=1S/C30H27F3N6O3/c1-16(40)22-13-38(26-7-2-18(9-21(22)26)36-19-10-34-15-35-11-19)14-28(41)39-12-17(31)8-27(39)30(42)37-25-6-3-20-23(32)4-5-24(33)29(20)25/h2,4-5,7,9-11,13,15,17,25,27,36H,3,6,8,12,14H2,1H3,(H,37,42)/t17-,25?,27+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
ACHILLION PHARMACEUTICALS, INC. US Patent					Assay Description Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...				US Patent US9598446 (2017) BindingDB Entry DOI: 10.7270/Q2ST7RWF
					More data for this Ligand-Target Pair