BDBM303367 US10138222, Example 92

SMILES: Cc1ccc(cc1-c1cnn(c1)-c1cncc(NC2CCNCC2)c1)C(=O)NC1CC1

InChI Key: InChIKey=PNQAJOUGTMFHFF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase RIPK2 (Homo sapiens (Human))	BDBM303367 (US10138222, Example 92) Show SMILES Cc1ccc(cc1-c1cnn(c1)-c1cncc(NC2CCNCC2)c1)C(=O)NC1CC1 Show InChI InChI=1S/C24H28N6O/c1-16-2-3-17(24(31)29-19-4-5-19)10-23(16)18-12-27-30(15-18)22-11-21(13-26-14-22)28-20-6-8-25-9-7-20/h2-3,10-15,19-20,25,28H,4-9H2,1H3,(H,29,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...				US Patent US10138222 (2018) BindingDB Entry DOI: 10.7270/Q2RV0QS2
					More data for this Ligand-Target Pair