BindingDB logo
myBDB logout

null

SMILES: Cc1ccc(cc1-c1cnn(c1)-c1cncc(NC2CCN(CC2)C2CCCOC2)c1)C(=O)NC1CC1

InChI Key: InChIKey=ZWMJTCLTMVKVNP-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303433   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-interacting serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM303433
PNG
(US10138222, Example 161)
Show SMILES Cc1ccc(cc1-c1cnn(c1)-c1cncc(NC2CCN(CC2)C2CCCOC2)c1)C(=O)NC1CC1
Show InChI InChI=1S/C29H36N6O2/c1-20-4-5-21(29(36)33-23-6-7-23)13-28(20)22-15-31-35(18-22)27-14-25(16-30-17-27)32-24-8-10-34(11-9-24)26-3-2-12-37-19-26/h4-5,13-18,23-24,26,32H,2-3,6-12,19H2,1H3,(H,33,36)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.5n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...

US Patent US10138222 (2018)


BindingDB Entry DOI: 10.7270/Q2RV0QS2
More data for this
Ligand-Target Pair