BDBM304030 5,7-Dimethyl-2-(2-phenyl-1H-benzo[d]imidazol-5-yl)-[1,2,4]triazolo-[1,5-a]pyrimidine::US10138245, Example 1

SMILES: Cc1cc(C)n2nc(nc2n1)-c1ccc2[nH]c(nc2c1)-c1ccccc1

InChI Key: InChIKey=FUBMEBBLWOMCRA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304030   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM304030 (5,7-Dimethyl-2-(2-phenyl-1H-benzo[d]imidazol-5-yl)...) Show SMILES Cc1cc(C)n2nc(nc2n1)-c1ccc2[nH]c(nc2c1)-c1ccccc1 Show InChI InChI=1S/C20H16N6/c1-12-10-13(2)26-20(21-12)24-19(25-26)15-8-9-16-17(11-15)23-18(22-16)14-6-4-3-5-7-14/h3-11H,1-2H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
CELON PHARMA S.A. US Patent					Assay Description Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...				US Patent US10138245 (2018) BindingDB Entry DOI: 10.7270/Q2M32XTX
					More data for this Ligand-Target Pair