BDBM304032 US10138245, Example 3

SMILES: Cc1cc(C)n2nc(nc2n1)-c1ccc2[nH]c(nc2c1)-c1ccccn1

InChI Key: InChIKey=ASIKOYRGPCQQHI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM304032 (US10138245, Example 3) Show SMILES Cc1cc(C)n2nc(nc2n1)-c1ccc2[nH]c(nc2c1)-c1ccccn1 Show InChI InChI=1S/C19H15N7/c1-11-9-12(2)26-19(21-11)24-17(25-26)13-6-7-14-16(10-13)23-18(22-14)15-5-3-4-8-20-15/h3-10H,1-2H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	279	n/a	n/a	n/a	n/a	n/a	n/a
CELON PHARMA S.A. US Patent					Assay Description Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...				US Patent US10138245 (2018) BindingDB Entry DOI: 10.7270/Q2M32XTX
					More data for this Ligand-Target Pair