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SMILES: Cc1cnc(C)c2nc(nn12)-c1ccc2[nH]c(nc2c1)-c1cccc(F)c1

InChI Key: InChIKey=MGXFLBNALZOGMM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304035   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))		BDBM304035
PNG
(2-[2-(3-Fluorophenyl)-1H-benzimidazol-5-yl]-5,8-di...)
Show SMILES Cc1cnc(C)c2nc(nn12)-c1ccc2[nH]c(nc2c1)-c1cccc(F)c1
Show InChI InChI=1S/C20H15FN6/c1-11-10-22-12(2)20-25-19(26-27(11)20)14-6-7-16-17(9-14)24-18(23-16)13-4-3-5-15(21)8-13/h3-10H,1-2H3,(H,23,24)
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US Patent
n/an/a 172n/an/an/an/an/an/a



CELON PHARMA S.A.

US Patent


Assay Description
Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...

US Patent US10138245 (2018)


BindingDB Entry DOI: 10.7270/Q2M32XTX
More data for this
Ligand-Target Pair