BDBM3041 23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4,6,8,11(15),17(22),18,20-nonaen-12-one::Go 7852::Indolocarbazole deriv.

SMILES: CN(C)CC(O)Cn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12

InChI Key: InChIKey=VKOHANATKXXKCN-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 3041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myosin light chain kinase, smooth muscle (Gallus gallus (chicken))	BDBM3041 (23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...) Show SMILES CN(C)CC(O)Cn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C26H26N4O2/c1-28(2)13-15(31)14-30-20-11-7-5-9-17(20)21-18-12-27-26(32)23(18)22-16-8-4-6-10-19(16)29(3)24(22)25(21)30/h4-11,15,31H,12-14H2,1-3H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	7.2	30
Tumor Biology Center					Assay Description The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Protein Kinase C (Rattus norvegicus (rat))	BDBM3041 (23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...) Show SMILES CN(C)CC(O)Cn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C26H26N4O2/c1-28(2)13-15(31)14-30-20-11-7-5-9-17(20)21-18-12-27-26(32)23(18)22-16-8-4-6-10-19(16)29(3)24(22)25(21)30/h4-11,15,31H,12-14H2,1-3H3,(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKC, activated by phosphatidylserine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich hi...				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine))	BDBM3041 (23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...) Show SMILES CN(C)CC(O)Cn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C26H26N4O2/c1-28(2)13-15(31)14-30-20-11-7-5-9-17(20)21-18-12-27-26(32)23(18)22-16-8-4-6-10-19(16)29(3)24(22)25(21)30/h4-11,15,31H,12-14H2,1-3H3,(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BLK (Mus musculus)	BDBM3041 (23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...) Show SMILES CN(C)CC(O)Cn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C26H26N4O2/c1-28(2)13-15(31)14-30-20-11-7-5-9-17(20)21-18-12-27-26(32)23(18)22-16-8-4-6-10-19(16)29(3)24(22)25(21)30/h4-11,15,31H,12-14H2,1-3H3,(H,27,32)	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of general tyrosine-specific protein kinase activity from murine B cell lysate				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Tyrosine-Specific Protein Kinase (Mus musculus (mouse))	BDBM3041 (23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...) Show SMILES CN(C)CC(O)Cn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C26H26N4O2/c1-28(2)13-15(31)14-30-20-11-7-5-9-17(20)21-18-12-27-26(32)23(18)22-16-8-4-6-10-19(16)29(3)24(22)25(21)30/h4-11,15,31H,12-14H2,1-3H3,(H,27,32)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of TPK is measured by its ability to transfer 32P from [gamma-32P]ATP to Poly(Glu,Tyr; 4:l)(sigma).				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM3041 (23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...) Show SMILES CN(C)CC(O)Cn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C26H26N4O2/c1-28(2)13-15(31)14-30-20-11-7-5-9-17(20)21-18-12-27-26(32)23(18)22-16-8-4-6-10-19(16)29(3)24(22)25(21)30/h4-11,15,31H,12-14H2,1-3H3,(H,27,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description Tested for inhibition of Myosin light chain kinase from chicken gizzard				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair
cGMP-Dependent Protein Kinase (Bos taurus (bovine))	BDBM3041 (23-[3-(dimethylamino)-2-hydroxypropyl]-3-methyl-3,...) Show SMILES CN(C)CC(O)Cn1c2ccccc2c2c3CNC(=O)c3c3c4ccccc4n(C)c3c12 Show InChI InChI=1S/C26H26N4O2/c1-28(2)13-15(31)14-30-20-11-7-5-9-17(20)21-18-12-27-26(32)23(18)22-16-8-4-6-10-19(16)29(3)24(22)25(21)30/h4-11,15,31H,12-14H2,1-3H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tumor Biology Center					Assay Description The activity of cGPK, activated by cGMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.				Bioorg Med Chem Lett 5: 55-60 (1995) Article DOI: 10.1016/0960-894X(94)00458-R BindingDB Entry DOI: 10.7270/Q2CF9N8C
					More data for this Ligand-Target Pair