BDBM304365 (R)-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine::US10144715, Compound 7-41

SMILES: CC(C)[C@@H]1CN(CCN1c1nc(ccc1Cl)C(F)(F)F)c1cccc(c1)S(C)(=O)=O

InChI Key: InChIKey=NLQZHFCXLSURKR-KRWDZBQOSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304365   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM304365 ((R)-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4...) Show SMILES CC(C)[C@@H]1CN(CCN1c1nc(ccc1Cl)C(F)(F)F)c1cccc(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C20H23ClF3N3O2S/c1-13(2)17-12-26(14-5-4-6-15(11-14)30(3,28)29)9-10-27(17)19-16(21)7-8-18(25-19)20(22,23)24/h4-8,11,13,17H,9-10,12H2,1-3H3/t17-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...				US Patent US10144715 (2018) BindingDB Entry DOI: 10.7270/Q2PV6NFD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM304365 ((R)-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4...) Show SMILES CC(C)[C@@H]1CN(CCN1c1nc(ccc1Cl)C(F)(F)F)c1cccc(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C20H23ClF3N3O2S/c1-13(2)17-12-26(14-5-4-6-15(11-14)30(3,28)29)9-10-27(17)19-16(21)7-8-18(25-19)20(22,23)24/h4-8,11,13,17H,9-10,12H2,1-3H3/t17-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...				US Patent US10144715 (2018) BindingDB Entry DOI: 10.7270/Q2PV6NFD
					More data for this Ligand-Target Pair