BDBM304533 (R)-1-(2-(difluoromethoxy)pyridin-4-yl)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine::US10144715, Compound 44-1

SMILES: CC(C)[C@@H]1CN(CCN1c1ccnc(OC(F)F)c1)c1ccc(F)c(c1)S(C)(=O)=O

InChI Key: InChIKey=CCZANINLKOMNJX-KRWDZBQOSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304533   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM304533 ((R)-1-(2-(difluoromethoxy)pyridin-4-yl)-4-(4-fluor...) Show SMILES CC(C)[C@@H]1CN(CCN1c1ccnc(OC(F)F)c1)c1ccc(F)c(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C20H24F3N3O3S/c1-13(2)17-12-25(14-4-5-16(21)18(10-14)30(3,27)28)8-9-26(17)15-6-7-24-19(11-15)29-20(22)23/h4-7,10-11,13,17,20H,8-9,12H2,1-3H3/t17-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...				US Patent US10144715 (2018) BindingDB Entry DOI: 10.7270/Q2PV6NFD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM304533 ((R)-1-(2-(difluoromethoxy)pyridin-4-yl)-4-(4-fluor...) Show SMILES CC(C)[C@@H]1CN(CCN1c1ccnc(OC(F)F)c1)c1ccc(F)c(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C20H24F3N3O3S/c1-13(2)17-12-25(14-4-5-16(21)18(10-14)30(3,27)28)8-9-26(17)15-6-7-24-19(11-15)29-20(22)23/h4-7,10-11,13,17,20H,8-9,12H2,1-3H3/t17-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...				US Patent US10144715 (2018) BindingDB Entry DOI: 10.7270/Q2PV6NFD
					More data for this Ligand-Target Pair