null
SMILES: CN(Cc1cccc2C(=CS(=O)(=O)c12)C1C(=O)[C@@H](N(CCC(C)(C)C)C1=O)C(C)(C)C)S(C)(=O)=O
InChI Key: InChIKey=IPAQBAGLGFYPKU-AVKWCDSFSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM30502 (benzo[b]thiophene-1,1-dioxide, 46) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 920 | n/a | 5.80E+3 | n/a | n/a | n/a | n/a |
Anadys Pharmaceuticals | Assay Description Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v... | Bioorg Med Chem Lett 18: 4181-5 (2008) Article DOI: 10.1016/j.bmcl.2008.05.083 BindingDB Entry DOI: 10.7270/Q2PC30Q5 | |||||||||||
More data for this Ligand-Target Pair |