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SMILES: CC(C)(C)CCN1[C@H](C(=O)C(C1=O)C1=CS(=O)(=O)c2c1cccc2CNS(C)(=O)=O)C(C)(C)C

InChI Key: InChIKey=IOKXFHXQRXIUEV-BDPMCISCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30503   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C virus genotype 1b (isolate BK) (HCV))		BDBM30503
PNG
(benzo[b]thiophene-1,1-dioxide, 47)
Show SMILES CC(C)(C)CCN1[C@H](C(=O)C(C1=O)C1=CS(=O)(=O)c2c1cccc2CNS(C)(=O)=O)C(C)(C)C |r,t:14|
Show InChI InChI=1S/C24H34N2O6S2/c1-23(2,3)11-12-26-21(24(4,5)6)19(27)18(22(26)28)17-14-34(31,32)20-15(9-8-10-16(17)20)13-25-33(7,29)30/h8-10,14,18,21,25H,11-13H2,1-7H3/t18?,21-/m1/s1
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PC cid
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Similars
Article
PubMed
n/an/a 240n/a 6.40E+3n/an/an/an/a



Anadys Pharmaceuticals



Assay Description
Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...

Bioorg Med Chem Lett 18: 4181-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.083
BindingDB Entry DOI: 10.7270/Q2PC30Q5
More data for this
Ligand-Target Pair